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Aktis Oncology

a16z portfolio company

Sr Manager, Facilities & Laboratory Ops

Location
Durham, NC, US
Compensation
USD 144,000–176,000 / year

About the role

Posted Oct 28, 2026

Aktis Oncology, Inc. is a clinical-stage oncology company focused on expanding the breakthrough potential of targeted radiopharmaceuticals to large patient populations, including those not addressed by existing platform technologies. Aktis’ most advanced program, AKY-1189, is a miniprotein radioconjugate targeting Nectin-4, with multi-indication potential across multiple tumor types, including locally advanced or metastatic urothelial cancer, breast cancer, non-small cell lung cancer, colorectal cancer, cervical cancer, and head and neck cancer. Aktis’ second pipeline program, AKY-2519, is a miniprotein radioconjugate targeting B7-H3 expressing tumors, including prostate, lung and other solid tumors. Aktis has a strategic collaboration with Eli Lilly and Company to leverage its miniprotein platform to develop novel radioconjugates outside of Aktis’ proprietary pipeline.

Aktis Oncology is seeking a Senior Manager, Facilities & Laboratory Operations to lead the strategic and day-to-day management of facilities, laboratory support, workplace services, vendors, and operational systems in a fast-paced environment. This is a hands-on position and is accountable for maintaining a safe, compliant, efficient, and fully operational workplace that supports scientific and administrative teams.

This role will report to the Senior Director, Facilities & Operations.

RESPONSIBILITIES

This role will drive several areas of strategic importance to Aktis:

FACILITIES & WORKPLACE OPERATIONS

  • Manage daily operations for laboratory, office, cafe, kitchen, conference room, and shared workplace areas.
  • Oversee Building Management System (BMS) performance, alarms, trends, and service-provider follow-up.
  • Administer employee and vendor badge access, access-level changes, and coordination with security providers.
  • Maintain cafe, kitchen, and workplace supplies, including ordering, receiving, stocking, and inventory control.
  • Coordinate preventive and corrective facility maintenance, repairs, inspections, and service visits.
  • Partner with landlords, property management, IT, EH&S, Finance, and internal stakeholders on site needs and projects.
  • Responsible for shipping and receiving both AM and PM.

LABORATORY OPERATIONS & EQUIPMENT SUPPORT

  • Provide operational support for laboratory equipment and serve as the primary liaison with equipment manufacturers and service vendors.
  • Work with equipment end user to facilitate contract and service-agreement renewal planning, quote collection, scope review, and routing for approval.
  • Coordinate equipment installation, preventive maintenance, repair, calibration, certification, and qualification activities, as applicable.
  • Work with vendors and laboratory stakeholders to schedule service while minimizing disruption to scientific operations.
  • Maintain accurate equipment records, service documentation, calibration status, and asset information.
  • Administrator of our Asset Management System (HOPEFULLY RAM), including asset records, work orders, maintenance and calibration schedules, documentation, and reporting. 

INVENTORY, PROCUREMENT & STOCKING

  • Manage laboratory consumable inventory and establish appropriate minimum, maximum, and reorder levels. Communicate supply chain issues with suitable options.
  • Order laboratory consumables through approved punch-out catalogs or purchasing systems.
  • Create purchase requisitions and purchase orders; track approvals, deliveries, invoice issues, and order status.
  • Receive, inspect, organize, and put away laboratory and workplace stock promptly.

GAS, WASTE & MATERIAL SERVICES

  • Manage laboratory gas ordering, delivery coordination, cylinder inventory, storage, change-outs, and vendor returns.
  • Coordinate and manage hazardous, biological, chemical, universal, recyclable, and general waste, as applicable.
  • Maintain waste service schedules, shipping papers, manifests, certificates, and related operational records.

VENDOR, CONTRACT & FINANCIAL ADMINISTRATION

  • Manage facility and laboratory service providers, including onboarding, scheduling, site access, performance, documentation, and issue resolution.

LIFE SAFETY, COMPLIANCE & INSPECTION READINESS

  • Coordinate required life-safety inspections and testing, including extinguishers, emergency lighting, eyewash stations, and safety showers.
  • Partner with EH&S and laboratory leaders to support audits, inspections, corrective actions, and continuous improvement.
  • Maintain SDS binders for all chemicals.

QUALIFICATIONS

  • Bachelor's degree in facilities management, engineering, life sciences, business administration, or a related field; equivalent relevant experience will be considered.
  • 7+ years of progressively responsible experience in facilities, laboratory operations, workplace operations, or a related function.
  • Experience supporting a research laboratory, biotechnology, pharmaceutical, medical device, or life sciences environment.
  • Demonstrated experience managing vendors, service contracts, maintenance programs, purchase orders, and inventory.
  • Working knowledge of building systems, laboratory service requirements, access control, life-safety systems, and waste coordination.
  • Strong organizational, communication, documentation, and problem-solving skills.
  • Ability to manage multiple priorities and perform effectively in a fast-changing startup environment.
  • Strong desire to be part of a mission‐oriented company leading transformative change for patients.
  • Proven demonstration of transparent communication and fostering open and diverse debate.
  • Ability to work with agility and manage ambiguity.
  • Personifies positive energy and exemplifies respect.
  • Hands-on, service-oriented leadership with a strong sense of ownership and urgency.
  • Ability to create structure in an evolving environment without overcomplicating processes.
  • Excellent vendor, stakeholder, and cross-functional relationship management.
  • Sound judgment, attention to detail, and consistent follow-through.
  • Commitment to safety, compliance, documentation, reliability, and continuous improvement.

PREFERRED QUALIFICATIONS

  • Experience administering Blue Mountain RAM or a comparable computerized maintenance or asset management system.
  • Experience with BMS platforms, access-control systems, regulated laboratories, and equipment calibration programs.
  • Knowledge of GxP, GLP, GMP, or other quality-system requirements, where applicable.
  • Experience supporting facility startup, expansion, laboratory construction, commissioning, or relocation projects.
  • Familiarity with laboratory gases, hazardous materials, waste streams, and vendor-managed compliance services.
  • DOT and RCRA certified.

PHYSICAL & WORK ENVIRONMENT REQUIREMENTS

  • Primarily onsite in laboratory and office environments.
  • Ability to move throughout the facility, access equipment areas, receive deliveries, and stock supplies.
  • Ability to lift 50lbs and move materials consistent with company safety requirements and applicable law.
  • Occasional after-hours availability may be required for alarms, emergencies, shutdowns, vendor work, or critical operational needs.


Aktis Oncology is an Equal Opportunity Employer and does not discriminate on the basis of race, religion, color, sex, gender identity or expression, sexual orientation, age, disability, national origin, veteran status, or any other basis covered by appropriate law. Aktis Oncology is committed to promoting and maintaining a work environment in which all applicants, employees, and other individuals are treated with dignity and respect, free from unlawful harassment, discrimination, or retaliation.

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At a glance

Location
Durham, NC, US
Compensation
USD 144,000–176,000 / year
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The company

Aktis Oncology

Aktis Oncology

Miniprotein-based alpha radiopharmaceuticals for oncology

IPO51–200 employeesBio + Health
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